Chemotherapeutic agent for use in preventing the advancement of testicular cancer. Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links. Synonyms: cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin, Briplatin, Cismaplat, Cisplatyl, Lederplatin, Neoplatin, Platamine, Platinex, Platiblastin, Platinol, Platinoxan CAS No: 15663-27-1 Molecular Formula: Pt(NH3)2Cl2 Molecular Weight: 300.05 Appearance: Yellow to orange crystalline powder Purity: 98-102% (HPLC) IR: Conforms to reference Melting Point: >220C (dec.) Absorbance (UV): 4.5 (Ratio) Trichloroammine Platinate: 1% Transplatin: 2% Platinum: ~65% Solubility: DMSO (25 mg/ml), Water (0.25g/100ml) at 25C, Ethanol (<1 mg/ml) at 25C, DMF (16mg/ml). Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
300.05
Purity:
98-102% (HPLC)
Form:
Yellow to orange crystalline powder
CAS Number:
[15663-27-1]
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