Chloromethyl polystyrene and styrene monomers are copolymerized in order to obtain the Merrifield resin. This method avoids the use of carcinogenic chloromethyl methyl ether. This resin is used in the synthesis of peptide acids using Boc strategy and can be cleaved using HF or TFMSA. Synonyms: Chloromethylated polystyrene, Chloromethylated stryene/divinylbenzene copolymer, Chloromethylated styrene-divinylbenzene resin, Copolymer of styrene and divinylbenzene, chloromethylated, Poly(styrene-co-vinylbenzyl chloride-co-divinylbenzene), Polystyrene crosslinked with divinylbenzene chloromethylated CAS No: 55844-94-5 Appearance: Pale to yellow to white polymer beads Infrared Spectrum: Conforms to reference Swelling in DCM: 5-9ml/g Swelling in DMF: 4-7ml/g DVB %: 1% DVB Mesh Size: 200-400 Substitution: 0.8-1.4meq/g Loss on Drying (1053C, 1.5h): 1% Storage and Stability: Store at RT. Stable for 6 months after receipt. Certificate of Origin: USA
Form:
Pale to yellow to white polymer beads
CAS Number:
[55844-94-5]
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