Selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. (IC50 values are 1.0, 0.6, 0.6, 18 and 22 uM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). Preferentially inhibits mutant over wild-type kinases (IC50 values are 1.5 vs 1000 nM for I338G v-src and v-src respectively). Synonyms: 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 1-NA-PP 1, 1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAS No: 221243-82-9 Molecular Weight: 317.39 Molecular Formula: C19H19N5 Purity (HPLC): 99% Appearance: White solid Solubility: DMSO to 20mM Method for Determining Identity: Proton NMR and Mass Spectrometric analysis Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. Hygroscopic and Light sensitive.
Molecular Weight:
317.39
Purity:
99% (HPLC)
Form:
White solid
CAS Number:
[221243-82-9]
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