Apoptotic, antiproliferative and antiangiogenic agent, in vitro and in vivo, acts via an estrogen receptor-independent mechanism. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-kappaB, and activation of JNK and AP-1 leading to Bcl-2 phosphorylation. Also upregulates death receptor 5 and binds to tubulin, inhibiting its assembly. CAS Number: 362-07-2
Purity:
99%
CAS Number:
[362-07-2]
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