Water-soluble GABAA antagonist. Methochloride salt of (+)-bicuculline. Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported. Synonym: [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride CAS Number: 53552-05-9 Molecular Formula: C21H20ClNO6 Molecular Weight: 417.85 Appearance: Off white solid Purity: 99% (HPLC) TLC [(Pyridine:Acetic acid:Water:Butanol [3:8:11:33])] Rf = 0.46 HPLC: >99.9% 1H NMR: Consistent with structure Mass Spectrum: Consistent with structure Microanalysis: Carbon Hydrogen Nitrogen Theoretical 56.7 5.21 3.15 Solubility: Water to 100mM PBS to 100mM Storage: RT
Molecular Weight:
417.85
Purity:
99% (HPLC)
Form:
Off white solid
CAS Number:
[53552-05-9]
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