BMS-309403 is a potent and selective fatty acid binding protein 4, adipocyte (FABP4) inhibitor (Ki values are <2, 250 and 350 nM for FABP4, FABP3 and FABP5 respectively). It decreases fatty acid uptake in adipocytes in vitro and reduces atherosclerotic lesion area in a mouse model of atherosclerosis. BMS309403 is an aromatic biphenyl azol compound that competes with fatty acids for the binding pocket of A-FABP with high specificity. Synonyms: 2-[[2-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1-biphenyl]-3-yl]oxy]-acetic Acid, FABP4 Inhibitor, Adipocyte Fatty-Acid-Binding Protein Inhibitor CAS No: 300657-03-8 Molecular Formula: C31H26N2O3 Molecular Weight: 474.55 Purity (HPLC): 98% Appearance: White to off-white powder Solubility: DMSO Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
474.55
Purity:
98% (HPLC)
Form:
White to off-white powder
CAS Number:
[300657-03-8]
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