Near-infrared probe that binds to Abeta40 aggregates (Kd = 38nM) and elicits an emission blue shift. Shown to bind to plaques in APP-PS1 transgenic mice, in vitro. Detects senile plaques in 19-month-old Tg2576 mice in vivo. Penetrates the blood-brain barrier. Synonyms: (T-4)-[(1E,6E)-1,7-Bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoroboron CAS No: 1193447-34-5 Molecular Formula: C23H25BF2N2O2 Molecular Weight: 410.26 Appearance: Crystalline solid Purity: 98% (HPLC) Solubility: DMSO [warming] Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
410.26
Purity:
98% (HPLC)
Form:
Crystalline solid
CAS Number:
[1193447-34-5]
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