ME 0328, CAS [[1445251-22-8]]
Catalog Number:
USB-255773
| Article Name: |
ME 0328, CAS [[1445251-22-8]] |
| Biozol Catalog Number: |
USB-255773 |
| Supplier Catalog Number: |
255773 |
| Alternative Catalog Number: |
USB-255773-10,USB-255773-50 |
| Manufacturer: |
US Biological |
| Category: |
Biochemikalien |
| Inhibitor of PARP-3 (IC50 = 0.89 µM). Displays selectivity for PARP-3 over PARP-1, PARP-2 and other ARDT enzymes (IC50 values are 6.3, 10.8 and >30 µM respectively). Enhances CRISPR-Cas9-mediated HER2 mutation frequency, resulting in increased reduction in proliferation of HER2-positive breast cancer cells. Cell permeable. Synonyms: 3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide CAS No: 1445251-22-8 Molecular Formula: C19H19N3O2 Molecular Weight: 321.37 Appearance: White solid Purity: 98% (HPLC) TLC Rf = 0.6 (Chloroform:Methanol [9:1]) 1H NMR: Consistent with structure Mass Spectrum: Consistent with structure Optical Rotation [alpha]D: -37.8 (Concentration = 0.65, Solvent = DMSO) Microanalysis: Carbon Hydrogen Nitrogen Theoretical 71.01 5.96 13.08 Found 70.83 5.94 13.03 Solubility: DMSO to 100 mM Storage: 4C |
| Molecular Weight: |
321.37 |
| Purity: |
98% (HPLC) |
| Form: |
White solid |
| CAS Number: |
[1445251-22-8] |
