Ouabain is a potent inhibitor of the Na+/K+-ATPase pump in cardiac and skeletal muscles. It has been shown to inhibit signal pathways that are involved in the regulation of cellular membrane potentials, such as the michaelis-menten kinetics. Ouabain has also been found to be effective against syncytial virus infection. Ouabain inhibits viral replication by inhibiting cellular protein synthesis and reducing cell number due to its cytotoxic effects on myocardial cells. Ouabain has also been found to inhibit neuronal death induced by alpha1-adrenergic receptor agonists, such as p2y receptors. Synonyms: 3-(6-Deoxy-alpha-L-mannopyranosyloxy)-1,5,11a,14,19-pentahydroxycard-20(22)-enolide, Acocantherin, Astrobain, Gratibain, Gratus strophanthin, Kombetin, Ouabain, (1beta,3beta,5beta,11alpha)-3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide Octahydrate, g-Strophanthin Octahydrate CAS No: 11018-89-6 Anhydrous: 630-60-4 Molecular Formula: C29H44O128H2O Molecular Weight: 728.77 Appearance: White to off-white solid Purity: 98% Melting Point: 178-185C Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly) Storage and Stability: Store at 4C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
728.77
Purity:
98%
Form:
White to off-white solid
CAS Number:
[630-60-4]
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