| Phalloidin is an F-actin stabilizing toxin and aids cytoskeletal deorganization in WPMY-1 cells. Phalloidin belongs to a class of toxins called phallotoxins, which are found in the death cap mushroom. Phalloidin is a promotes actin polymerization. Decreases dissociation rate constant for actin subunits from filament ends, lowers critical concentration for polymerization. Sequence: ATCXAWL (Modifications: Cyclic Cys-3-Trp-6, X=Hyp, D-Thr-2) Synonyms: 28-(2,3-dihydroxy-2-methylpropyl)-18-hydroxy-34-(1-hydroxyethyl)-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octazapentacyclo[12.11.11.03,11.04,9.016,20]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone, Cyclo[L-alanyl-D-threonyl-L-cysteinyl-(4S)-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-(4R)-4,5-dihydroxy-L-leucyl] Cyclic (36)-thioether, 18,9-(Iminoethaniminoethaniminoethaniminomethano)-17H-pyrrolo[1,2:5,6][1,5,8,11]thiatriazacyclopentadecino[15,14-b]indole Cyclic Peptide Derivative, NSC 523214, NSC-523214, NSC523214 CAS No: 17466-45-4 Molecular Formula: C35H48N8O11S Molecular Weight: 788.87 Appearance: White to off-white powder Purity: 90% Solubility: Soluble to 1mg/ml in water, DMSO (Slightly) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
