Rhosin hydrochloride is a Rho GTPase inhibitor. It acts by inhibiting binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Synonyms: D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide Hydrochloride, Rhosin hydrochloride, Rhosin HCl, G04 CAS No: 1281870-42-5 Free Base: 1173671-63-0 Molecular Formula: C20H18N6OHCl1.25 H2O Molecular Weight: 417.38 Purity: 98% Appearance: Yellow solid Solubility: Soluble to 20mM in water with gentle warming and to 100mM in DMSO Method for Determining Identity: Proton NMR and Mass Spectrometric Analysis Specific Rotation: [a]D= -43.6 (c=1, DMSO) Elemental Analysis: Calculated: %C: 57.55, %H: 5.19, %N: 20.14 Storage and Stability: May be stored at 4C for short-term only. Store at -20C. Stable for 6 months after receipt at -20C. Light sensitive.
Molecular Weight:
417.38
CAS Number:
[1281870-42-5]
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