Potent and selective extracellular signal-related kinase 2 (ERK2) inhibitor (Ki values are <2, 395, 540 and 852 nM for ERK2, GSK-3, Aurora Kinase A and Cdk2 respectively). Potently blocks proliferation of HT29 cells (IC50 = 48 nM). Orally bioavailable. CAS Number: 896720-20-0 Molecular Weight: 500.35 Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol Molecular Formula: C24H20Cl2FN5O2 Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
500.35
Purity:
>98%
CAS Number:
[896720-20-0]
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