Spectinomycin Hydrochloride Pentahydrate, CAS [[1695-77-8]]

Product Overview

• Article Name: Spectinomycin Hydrochloride Pentahydrate, CAS [[1695-77-8]]
• Biozol Catalog Number: USB-257390
• Supplier Catalog Number: 257390
• Alternative Catalog Number: USB-257390-1,USB-257390-5,USB-257390-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections.[1] It is given by injection into a muscle.[1] Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class and works by stopping the making of protein by certain bacteria.[1]vcSpectinomycin was discovered 1961.[2] It is on the World Health Organizations List of Essential Medicines. Spectinomycin binds to the 30S subunit of the bacterial ribosome and interrupts protein synthesis. One form of resistance has emerged in the 16S ribosomal RNA in Pasteurella multocida.[6]. Spectinomycin is in aminocyclitol class, closely related to the aminoglycosides, produced by the bacterium Streptomyces spectabilis. Spectinomycin is produced in nature by many organisms including cyanobacteria and various plant species. It is present in the genome or plastome of many plastids as the spc operon, which is usually two to 10 amino acids long. The difference in size may be due to the elimination of obsolete genes or the takeover of its function by nuclear genes. Spectinomycin is mainly produced by organisms as a defence mechanism against predators. Synonyms: (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-Decahydro-4a,7,9- trihydroxy-2-methyl-6,8-bis(methylamino)-4H-pyrano[2,3-b][1,4] benzodioxin-4-one Hydrochloride Pentahydrate CAS No: 1695-77-8 22189-32-8 Molecular Formula: C14H24N2O7HCl 5H2O Molecular Weight: 458.91 Appearance: White to off-white crystalline powder 1H-NMR: Conforms to reference Activity: ~780 U/mg Melting Point: 210C Water: 16-20% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 458.91
• Purity: Activity: ~780 U/mg
• Form: White to off-white crystalline powder
• CAS Number: [1695-77-8]