APAD is an NAD analog with higher oxidation potential than NAD. It can substitute for NAD as a hydrogen-accepting cofactor in many dehydrogenase reactions, e.g. lactate dehydrogenase from Toxoplasma, Clonorchis, and Plasmodium, bacterial lipoamide dehydrogenase, as well as mammalian dehydrogenases. It can also act as a proton acceptor in various transhydrogenation reactions with NADH or NADPH. Synonyms: APAD, adenosine 5-(trihydrogen diphosphate), P5-ester with 3-acetyl-1-beta-D-ribofuranosylpyridinium, inner salt CAS No: 86-08-8 Molecular Formula: C22H28N6O14P2 Molecular Weight: 662.44 Purity: 90% (HPLC) Appearance: White to off-white crystalline powder Water (Karl Fischer): 8% Storage and Stability: Powder may be stored at -20C. Stable for 6 months aftyer receipt at -20C. Aqueous solutions of APAD can be prepared by directly dissolving the crystalline solid in aqueous buffers. We do not recommend storing the aqueous solution for more than one day. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molecular Weight:
662.44
Purity:
90% (HPLC)
Form:
White to off-white crystalline powder
CAS Number:
[86-08-8]
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