Berberine is a natural compound that has been shown to have anti-inflammatory and anticancer properties. It is the main component of berberine sulfate, which can be found in plants such as Coptis chinensis and goldenseal. Berberine sulfate has been shown to inhibit skin tumor formation by inhibiting nuclear DNA synthesis and tumor cell growth. Berberine sulfate also inhibits the production of p-nitrophenyl phosphate, a chemical that is used as an indicator for bacterial growth. Berberine sulfate binds to DNA polymerase and inhibits its activity, thereby preventing transcription of DNA into RNA. This compound can be used in chromatographic analysis and optical sensor systems to detect bacterial infections. Synonyms: Berberine hydrogen sulfate, Natural Yellow 18, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)Berbinium Sulfate, Berberine Bisulfate, NSC 150444 CAS No: 633-66-9 Molecular Formula: C20H18NO4HSO4 Molecular Weight: 433.43 Appearance: White to yellow powder Purity: 95% (HPLC) 1H-NMR: Conforms to reference Solubility: DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic.
Molecular Weight:
433.43
Purity:
95% (HPLC)
Form:
White to yellow powder
CAS Number:
[633-66-9]
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