Sulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto-beta-boswellic acid (KBA) and 3-acetyl-11-keto-beta-boswellic acid (AKBA) with organic anion transporter OATP1B3. Sulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20. Synonyms: Bromsulfalein disodium salt hydrate, Bromothalein disodium salt hydrate, Sulfobromophthalein disodium salt hydrate, BSP, disodium 2-hydroxy-5-1z-4-oxo-3-sulfonatocyclohexa-2,5-dien-1-ylidene 2,3,4,5-tetrabromo-6-carboxyphenyl methyl benzenesulfonate tetrahydrate CAS Number: 123359-42-2 Molecular Formula: C20H8Br4O10S22Na Molecular Weight: 837.99 Appearance: White to off-white to grey or light brown powder Water Content: 8% Sodium Content: 2% Storage and Stability: Store at 4C. Stable for 6 months after receipt. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molecular Weight:
837.99
Form:
White to off-white to grey or light brown powder
CAS Number:
[123359-42-2]
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