| Chlorogenic acid is a derivative of caffeic acid and quinic acid, it has an antioxidant activity. Chlorogenic acid has been combined with gadolinium to develop a therapeutic and diagnostic nanodelivery system for MRI imaging. In a rat model of diabetes mellitus, chlorogenic acid counteracted the alterations in lipid profiles typical of type-2 diabetes, especially when administered in combination with tetrahydrocurcumin. In mice fed with a high-fat diet, the consumption of chlorogenic acid resulted in an anti-obesity action that lowered the blood levels of cholesterol and triglycerides. In humans, it is readily absorbed in the intestinal tract. Synonyms: (1S,3R,4R,5R)-3-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyloxy]-1,4,5-trihydroxycyclohexanecarboxylic Acid, 3-(3,4-Dihydroxycinnamoyl)quinic Acid, 3-Caffeoylquinic Acid, 3-O-(3,4-Dihydroxycinnamoyl)-D-quinic Acid, 3-O-Caffeoylquinic Acid, Heriguard, NSC 407296, NSC 70861, [1S-(1alpha,3beta,4alpha,5alpha)]-3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyloxy]-1,4,5-trihydroxycyclohexanecarboxylic Acid, Caffetannic acid, Helianthic acid, Igasuric acid CAS No: 327-97-9 Molecular Formula: C16H18O9 Molecular Weight: 354.31 Appearance: White to off-white powder Purity: 98% (HPLC) Melting Point: 192-195C Loss on Drying: 5% Heavy Metals: 0.001% Sulfate (SO42-): 0.5% Chlorate (Cl-): 0.0001% Phosphate (PO43-): 0.0001% Lead (Pb): 0.0001% Arsenic (As): 0.0002% Cadmium (Cd): 0.0001% Yeast and Mold: 50cfu/g E. coli: Absent Pseudomonas aeruginosa: Absent Salmonella: Negative Staphylococcus aureus: Negative Mesh Size: 100% pass 80 mesh Ash: 3% Solubility: DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap |
