Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes. Phenothiazine antipsychotic, D2 dopamine receptor antagonist, H1 histamine receptor antagonist, inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase. Synonyms: 2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine hydrochloride, CPZ, Largactil CAS No: 69-09-0 Molecular Formula: C17H20Cl2N2S Molecular Weight: 355.33 Purity: 99.5% (Titration) Appearance: White or milky white crystalline powder Infrared Spectrum: Conforms to reference Melting Point: 194-198C Clarity and Color: The solution should be clear and colorless or lighter than No.1 turbidity standard solution and lighter than Yellow No.3 or yellow green No.3 standard colorimetric solution Odor: Slight odor Loss on Drying: 0.5% Related Substances: Single impurity: 0.5% Total impurities: 1% Residue on Ignition: 0.1% Solubility: Soluble in water, ethanol or chloroform. Insoluble in ether or benzene Residual Solvents: Toluene: 0.089% Isopropanol: 0.5% Mold and Yeast: 100cfu/g E. coli: Not Detected Microbial Count: 1000cfu/g (TABC) Storage and Stability: Store at 4C. Stable for 6 months after receipt. Hygroscopic
Molecular Weight:
355.33
CAS Number:
[69-09-0]
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