Cyclo(-Gly-L-His) cyclic structure offers resistance to degradation, and its studied for potential therapeutic uses in cancer and as a model for peptide drug delivery systems. Cyclo(His-Gly) inhibited the growth of MCF-7 cancer cells in vitro and showed antithrombotic effects. Cyclo-(His-Gly), which is related to anorexigenic peptide, was shown to inhibit release of catecholamine and norepinephrine in vitro significantly. The diketopiperazine could play a role in the hypothalamic modulation of appetite suppressant circuitry. Synonyms: Cyclo(-Gly-His), (S)-3-((1H-imidazol-5-yl)methyl)piperazine-2,5-dione CAS No: 15266-88-3 Molecular Formula: C8H10N4O2 Molecular Weight: 194.19 Purity: 98% (HPLC) Appearance: White to off-white powder Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
194.19
CAS Number:
[15266-88-3]
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