Eosine-5-isothiocyanate is a fluorescent probe that has affinity for the interstitium of the kidney. This compound inhibits the transport of organic compounds across the renal tubular epithelium, and it is used as a marker for renal function. Eosine-5-isothiocyanate binds to molybdate with high affinity and can be used to measure its concentration in blood plasma. The inhibitory potency of eosine-5-isothiocyanate on carboxylates was tested by perfusing phenolphthalein through a rats kidneys. Phenoxy dicarboxylates were found to be more potent inhibitors than phenoxy monocarboxylates, but not as potent as eosine-5-isothiocyanate itself. The spectrum of eosine-5-isothiocyanate is in the visible range. Synonyms: EITC, 2,4,5,7-Tetrabromo-3,6-dihydroxy-5-isothiocyanatospiro[isobenzofuran-1 (3H),9-[9H]xanthen]-3-one, Eosin Isothiocyanate CAS No: 60520-47-0 Molecular Formula: C21H7Br4NO5S Molecular Weight: 704.97 Purity (HPLC): 98% Appearance: Orange to red powder 1H-NMR: Conforms to reference Storage and Stability: Store at -20C. Stable for 6 months after receipt.
Molecular Weight:
704.97
CAS Number:
[60520-47-0]
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