Potent, selective and competitive inhibitor of sodium-glucose cotransporter SGLT2, which is implicated in renal glucose reabsorption. The compound increases urinary glucose excretion, helps decrease hyperglyceamia and maintains glucose homeostasis in diabetic individuals. It has been associated with weight loss, lower blood pressure and decreased glycated haemoglobin. Animal studies suggest that empagliflozin preserves regeneration of beta-cells in pancreatic Langerhans islets. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol, BI 10773, Jardiance CAS No: 864070-44-0 Molecular Formula: C23H27ClO7 Molecular Weight: 450.91 Purity (HPLC): 98% Appearance: White to off-white solid Melting Point: 151-153C (lit) Method for Determining Identity: Proton NMR Spectroscopic Storage and Stability: Powder is stable for 6 months after receipt at 4C.
Molecular Weight:
450.91
Purity:
98% (HPLC)
Form:
White to yellow solid.
CAS Number:
[864070-44-0]
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