DL-4-Hydroxy-2-Ketoglutarate Lithium Salt, CAS [[1187-99-1]]

Product Overview

• Article Name: DL-4-Hydroxy-2-Ketoglutarate Lithium Salt, CAS [[1187-99-1]]
• Biozol Catalog Number: USB-279270
• Supplier Catalog Number: 279270
• Alternative Catalog Number: USB-279270-10,USB-279270-50
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

DL-4-Hydroxy-2-ketoglutarate dilithium salt (DL4KG) is a lysine analogue that is used as a substrate for the enzyme aldolase. DL4KG has a hydroxyl group, which can react with the amino group of lysine residues on proteins to produce an unstable intermediate. This process eventually leads to the production of glutamate and glyceraldehyde 3-phosphate, which are needed in the synthesis of ATP. DL4KG has been shown to be an inhibitor of bacterial enzymes such as glutamate dehydrogenase, which catalyzes the conversion of L-glutamic acid to L-glutamine. Inhibition by DL4KG has been demonstrated in vitro at concentrations between 2-10mM. Synonyms: 4-Hydroxy-2-oxoglutaric acid lithium salt, DL-KHG Li CAS No: 1187-99-1 Free Acid: 162.10 Molecular Formula: C5H6O6xLi+ Molecular Weight: 162.10 Free Acid Purity: 90% (TLC) Appearance: White to off-white powder Water: 15% Method of Determining Identity: Proton NMR Spectometry Lithium (anhydrous basis): 3.9-8.4% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Bottomless glass bottle. Contents are inside inserted fused cone. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 162.1
• Purity: 90% (TLC)
• Form: White to off-white powder
• CAS Number: [1187-99-1]