Levomefolic acid is a derivative of folic acid and belongs to the group of dinucleotide phosphates. It has been shown to have a protective effect against blood clots, and is used in the treatment of pernicious anaemia, megaloblastic anaemia, and leukopenia. Levomefolic acid also inhibits energy metabolism in bacteria. Its mode of action is not fully understood but it has been demonstrated that it inhibits enzyme activities such as methylenetetrahydrofolate reductase (MTHFR) and 5-methyltetrahydrofolate cyclohydrolase. The production of DNA nucleotides has also been shown to be inhibited by the drug. Levomefolic acid has also been shown to have an effect on redox potentials in cancer cell lines. In addition, it has been found that levomefolic acid can be transferred from maternal blood to human serum. Synonyms: N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid, (6S)-5-Methyltetrahydrofolic acid, 5-Methyl-(6S)-tetrahydrofolic acid CAS No: 31690-09-2 Molecular Formula: C20H25N7O6 Molecular Weight: 459.46 Appearance: White to light yellow powder Purity: 95% Storage and Stability: Store at 4C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
459.46
Purity:
95%
Form:
White to light yellow powder
CAS Number:
[31690-09-2]
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