Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade.1 It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases.1 In various animal arterial and venous thrombosis models, rivaroxaban is reported to inhibit thrombin formation without prolonging bleeding time and has been approved for clinical use as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms. Synonyms: 5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide, BAY 59-7939 CAS Number: 366789-02-8 Molecular Formula: C19H18ClN3O5S Molecular Weight: 435.88 Appearance: Supplied as a white to off-white crystalline powder. Purity: 98% Melting Point: 228-229C (lit) Loss on Drying: 0.5% Storage: Store at 4C. Stable for 6 months after receipt.
Molecular Weight:
435.88
Purity:
98% (HPLC)
Form:
Supplied as a white to off-white crystalline powder
CAS Number:
[366789-02-8]
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