A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells. Applications: Suitable for use as a histone deacetylase inhibitor. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Synonyms Butanoic Acid Sodium Salt, Butyric acid Sodium Salt, Adimix, Butyrate Sodium, Gustor XXI B 70, Sodium Butanoate, CAS Number: 156-54-7 Molecular Formula: C4H7NaO2 Molecular Weight: 110.09 Appearance: Supplied as a white to off-white powder Purity: 99% Loss on Drying: 5% Melting Point: 251-252C Storage Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive. Store under inert atmosphere.
Molecular Weight:
110.09
Purity:
99%
Form:
Supplied as a white to off-white powder
CAS Number:
[156-54-7]
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