PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2-deoxy-2-alpha-fluoro-beta-C-methyluridine-5-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: Isopropyl(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate, N-[[P(S),2R]-2-deoxy-2-fluoro-2-methyl-P-phenyl-5-uridylyl]-1-methylethyl Ester L-Alanine, GS-7977, PSI-7977 CAS Number: 1190307-88-0 Molecular Formula: C22H29FN3O9P Molecular Weight: 529.45 Appearance: White to yellow powder Purity: 99% (HPLC) Identity (1H NMR): Conforms to structure Water (KF): 1% Storage and Stability: Store at 4C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
529.45
Purity:
99% (HPLC)
Form:
White to yellow powder
CAS Number:
[1190307-88-0]
* VAT and and shipping costs not included. Errors and price changes excepted
