Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine, epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide syntheses. Chemically, its structure is that of a reduced pteridine derivative. Synonyms: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride, 6R-BH4, Sapropterin, Sapropterin dihydrochloride, BioMarin T 1401, Biopten, Kuvan, SUN 0588, Shiratori SN 0588 CAS No: 69056-38-8 62989-33-7 Molecular Formula: C9H15N5O32(HCl) Molecular Weight: 314.17 Appearance: White to light yellow powder Purity: 96% 1H-NMR Spectrum: Conforms to reference Loss on Drying: 2% Melting Point: >202C (dec.) Solubility: Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
314.17
Purity:
96% (HPLC)
Form:
White to light yellow powder
CAS Number:
[69056-38-8]
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