D-Glucose, a naturally occurring monosaccharide found in plants, is the primary energy source for living organisms.1 It is utilized as a metabolic intermediate by cells for either aerobic or anaerobic respiration. D-Glucose exists in two cyclic forms, alpha-D-glucose and beta-D-glucose, based on the position of the substituent at the anomeric center.2 alpha-D-Glucose is the monomer unit in starch, whereas beta-D-glucose is the monomer unit in cellulose.2 When one of these anomers is added to solution, it undergoes reversible epimerization to the other via an open-chain form, during which the specific rotation of the solution changes gradually until it reaches equilibrium. The existence of multiple binding modes of this single monosaccharide has been studied as a model scaffold to design compounds with increased probability of ligand binding.3 Synonyms: beta-D-glucopyranose, (2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol CAS Number: 492-61-5 Molecular Formula: C6H12O6 Molecular Weight: 180.15 Purity: 98% Appearance: White to off-white crystalline powder Solubility: A stock solution may be made by dissolving the beta-D-glucose in the solvent of choice. beta-D-Glucose is soluble in organic solvents such as DMSO and dimethyl formamide, which should be purged with an inert gas. The solubility of beta-D-glucose in these solvents is approximately 20 and 10 mg/ml, respectively. Further dilutions of the stock solution into aqueous buffers or isotonic saline should be made prior to performing biological experiments. Ensure that the residual amount of organic solvent is insignificant, since organic solvents may have physiological effects at low concentrations. Organic solvent-free aqueous solutions of beta-D-glucose can be prepared by directly dissolving the crystalline solid in aqueous buffers. The solubility of beta-D-glucose in PBS, pH 7.2, is approximately 10mg/ml Do not store the aqueous solution for more than one day. Storage and Stability: Lyophilized powder is stable for 6 months after receipt at -20C under inert atmosphere.
Molecular Weight:
180.15
Purity:
98%
Form:
White to off-white crystalline powder
CAS Number:
[492-61-5]
* VAT and and shipping costs not included. Errors and price changes excepted
