UDP-D-Glucuronide Ammonium Salt, CAS [[43195-60-4]]

Product Overview

• Article Name: UDP-D-Glucuronide Ammonium Salt, CAS [[43195-60-4]]
• Biozol Catalog Number: USB-295071
• Supplier Catalog Number: 295071
• Alternative Catalog Number: USB-295071-100,USB-295071-250,USB-295071-500
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

UDP-D-glucuronide ammonium salt is a drug that is used for the treatment of estrogen-dependent cancers. It is an inhibitor of human UDP-glucuronosyltransferase, an enzyme that catalyzes the glucuronidation of estrone and other substrates. The binding affinity of UDP-D-glucuronide ammonium salt can be increased by mutating the enzyme to increase its kinetic rate. This drug has been shown to inhibit estrogen production in recombinant human liver cells as well as in human liver cells. Mutations in the gene encoding this enzyme have also been associated with variations in estrogen levels, specifically high rates. Synonyms: UDP-GlcA, UDPGA, Uridine-diphosphate-glucuronic acid ammonium salt, Uridine[5']diphospho[1]-alpha-D-glucopyranosuronic acid CAS No: 43195-60-4 Molecular Formula: C15H22N2O18P2xNH3 Molecular Weight: 580.29 (free acid) Appearance: White to off-white powder Purity: 98% Water (KF): 10% Phosphorus (Dry basis): 9-11% Ammonia (Dry basis): 1-10% Solubility: Water, 50mg/ml Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 580.29
• Purity: 98%
• Form: White to off-white powder
• CAS Number: [43195-60-4]