Potent and selective inhibitor of influenza A and B sialidases (neuraminidases). This compound is a sialic acid analogue that occupies viral neuraminidase active site, inhibits enzymes hydrolytic activity and cleavage of sialic acid residues from host cell surface glycans. It therefore prevents shedding newly produced virions from infected cell surface and reduces infection of surrounding cells. Synonyms: Relenza, GG 167, 2,3-Didehydro-2,4-dideoxy-4-guanidine-N-acetyl-acetyl-D-neuraminic acid, 4-Guanidino-2,4-dideoxy-2,3-didehydro-N-acetylneuraminic acid, 5-Acetamino-2,6-anhydro-4-guanidino-3,4,5-trideoxy-D-galcto-non-enoic acid CAS No: 551942-41-7 Molecular Formula: C12H22N4O8 Molecular Weight: 332.31 Purity (HPLC): 98% Appearance: White to off-white powder Identity (IR): Conforms to structure Melting Point: As Reported Specific Optical Rotation ([alpha]20 (c=0.9, H O): D. 2): +33 to +42 Storage and Stability: Store at -20C. Stable for 6 months after receipt.
Molecular Weight:
350.33
CAS Number:
[551942-41-7]
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