Colominic acid is used to study protein polysialylation processes. It is a substrate for CMP-NeuAc:(NeuAcalpha28)n (colominic acid) sialyltransferase. Naturally isolated from the cell wall of E. coli and animals, gives a red color which has an absorption maximum at 530nm. Colominic acid sodium salt (Polysialic acid sodium salt) possesses anti-bacterial activity. Colominic acid (polysialic acid) is a linear small polysaccharide containing alpha-2,8-linked sialic acid (neurominic acid) with (n = 8 to >100) residues. Polysialic acid is an unusual post translational modification polysaccharide that is widely expressed in nature in bacterial capsules, fish, sea urchin eggs, embryonic tissues, amphibians, animal and human brains, and in a various cancers. The major carrier of polysialic acids in mammals is the neural cell adhesion molecule (a glycoprotein that belongs to the immunoglobulin superfamily). Synonyms: Poly[2,8-(N-acetylneuraminic acid sodium salt)] CAS No: 70431-34-4 Molecular Formula: (C11H16NNaO8)n Molecular Weight: ~30,000 Appearance: White to off-white solid Purity: As reported Solubility: H2O, 50mg/ml Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
30000
Purity:
As reported
Form:
White to off-white solid
CAS Number:
[70431-34-4]
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