Dioscin is a natural compound that has been shown to have cytotoxic effects on human tumor cells. Dioscin has been found to be an apoptosis-inducing factor, which activates the mitochondrial pathway of apoptosis. It has also been shown to inhibit the proliferation of 3T3-L1 preadipocytes and HL-60 cells by affecting the bcl-2 protein and toll-like receptor pathways. Dioscin is effective in treating myocardial infarcts, as well as other injuries such as squamous cell carcinoma. Synonyms: (+)-Dioscin, 3-O-beta-D-alpha-L-Rhamnopyranosyl(14)-[alpha-L-rhamnopyranosyl(12)]-beta-D-glucopyranoside-diosgenin, Collettiside III, Dioscine, Diosgenin 3-O-alpha-L-Rhamnopyranosyl-(12)-[alpha-L-rhamnopyranosyl-(14)]-beta-D-glucopyranoside, Diosgenin 3-O-alpha-L-Rhamnopyranosyl-(14)-[alpha-L-rhamnopyranosyl-(12)]-beta-D-glucopyranoside, Diosgenin bis-alpha-L-rhamnopyranosyl-(12 and 14)-beta-D-glucopyranoside, Paris III, Polyphyllin III, (3beta,25R)-Spirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(12)-O-[6-deoxy-alpha-L-mannopyranosyl-(14)]-beta-D-glucopyranoside CAS No: 19057-60-4 Molecular Formula: C45H72O16 Molecular Weight: 869.04 Appearance: White to off-white powder Purity: 98% (HPLC) Loss on Drying: 5% Sulfated Ash: 1% Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
869.04
Purity:
98% (HPLC)
Form:
White to off-white powder
CAS Number:
[19057-60-4]
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