TRIM24, Recombinant, Human, aa896-1014, His-Tag (TIF1, Tripartite Motif Containing 24)
Catalog Number:
USB-298485
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| Article Name: | TRIM24, Recombinant, Human, aa896-1014, His-Tag (TIF1, Tripartite Motif Containing 24) |
| Biozol Catalog Number: | USB-298485 |
| Supplier Catalog Number: | 298485 |
| Alternative Catalog Number: | USB-298485-100 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]. Source: Recombinant protein corresponding to aa896-1014 from human bromodomain tripartite motif containing 24, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~15kD AA Sequence: MHHHHHHGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLS TIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLY PEKRFPKPE Applications: Suitable for use in the study of bromodomain binding assays, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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