Ingenol 3-Angelate is a diterpenoid ester isolated from Euphorbia peplus that induces rapid cell death with keratinocytes and some cancer cell lines. Ingenol 3-Angelate is a protein kinase C activator that displays potent antileukemic activity. Ingenol 3-Angelate (ingenol mebutate) is used for treatment of actinic keratosis. Solubility: DMSO: soluble15mg/ml, clear Loss on Drying: 3% Identification Method: Proton NMR Spectroscopic and Mass Spectrometric Analysis Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive
Molecular Weight:
430.53
Purity:
98% (HPLC)
Form:
Supplied as a white powder
CAS Number:
[75567-37-2]
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