Nesfatin-1, is a multi-functional peptide hormone with an approximate MW of 9.8kD and a half-life of 23.5 minutes. This peptide is found in three different forms, nesfatin-1, nesfatin-2 and nesfatin-3, all three of which are formed from the precursor NUCB2 by proteolytic processing. The 30-amino acid middle segment of nesfatin-1 (M30) is responsible for limiting food intake, while the exact physiological role of nesfatin-2 and nesfatin-3 are unknown. Molecular Weight: ~9424.15 Sequence: pGlu-Glu-Val-Gly-Arg-Leu-Arg-Met-Leu-Ile-Lys-Ala-Lys-Leu-Asp-Ser-Leu-Gln-Asp-Ile-Gly-Met-Asp- His-Gln-Ala-Leu-Leu-Lys-Gln-Phe-Asp-His-Leu-Asn-His-Leu-Asn-Pro-Asp-Lys-Phe-Glu-Ser-Thr-Asp- Leu-Asp-Met-Leu-Ile-Lys-Ala-Ala-Thr-Ser-Asp-Leu-Glu-His-Tyr-Asp-Lys-Thr-Arg-His-Glu-Glu-Phe- Lys-Lys-Tyr-Glu-Met-Met-Lys-Glu-His-Glu Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
9424.15
Purity:
~95% (HPLC)
Form:
Supplied as a white powder.
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