C-C motif chemokine 18, active (CCL18), Recombinant, Human
Biozol Catalog Number:
USB-347951
Supplier Catalog Number:
347951
Alternative Catalog Number:
USB-347951-10, USB-347951-100
Manufacturer:
US Biological
Category:
Molekularbiologie
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. Full length recombinant protein corresponding to aa21-89 of human mature CCL18, tag free expressed in E. coli. Swiss/UniProt Accession: P55774. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10ng/ml. Sequence: AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA Molecular Weight: 7.9kD PubMed ID: 9233607, 9570561, 9192897, 10049593, 10087196, 19054851, 15489334, 9129202, 11745396, 11978786, 23742785 Gene Name: CCL18, AMAC1, DCCK1, MIP4, PARC, SCYA18 Swiss Prot: P55774 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
