C-X-C motif chemokine 6, active (CXCL6), Recombinant, Human
Biozol Catalog Number:
USB-348013
Supplier Catalog Number:
348013
Alternative Catalog Number:
USB-348013-5
Manufacturer:
US Biological
Category:
Molekularbiologie
Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50ng/ml. Sequence: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN Molecular Weight: 7.9kD PubMed ID: 9164944, 14702039, 15815621, 15489334, 9057843, 8399143, 8423327, 18443119 Gene Name: CXCL6,GCP2,SCYB6 Swiss Prot: P80162 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
