Glial cell line-derived neurotrophic factor, active (GDNF), Recombinant, Human
Biozol Catalog Number:
USB-348058
Supplier Catalog Number:
348058
Alternative Catalog Number:
USB-348058-10
Manufacturer:
US Biological
Category:
Molekularbiologie
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. {ECO:0000269|PubMed:8493557}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.1ng/ml, corresponding to a specific activity of > 5.0x10e7 IU/mg. Sequence: SPDKQMAVLP RRERNRQAAA ANPENSRGKG RRGQRGKNRG CVLTAIHLNV TDLGLGYETK EELIFRYCSG SCDAAETTYD KILKNLSRNR RLVSDKVGQA CCRPIAFDDD LSFLDDNLVY HILRKHSAKR CGCI Molecular Weight: 30.1kD PubMed ID: 8493557, 7867768, 15372022, 15489334, 10e366742, 9811930, 8988018, 22081608, 9359036, 19478429, 8968758, 8896568, 8896569, 9497256, 10917288 Gene Name: GDNF Swiss Prot: P39905 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
