BAIAP2, Recombinant, Human, aa1-522, His-Tag (BAI1-associated protein 2)
Biozol Catalog Number:
USB-349713
Supplier Catalog Number:
349713
Alternative Catalog Number:
USB-349713-100,USB-349713-500
Manufacturer:
US Biological
Category:
Molekularbiologie
BAI1-associated protein 2, also known as BAIAP2, is a ubiquitous regulator of the actin cytoskeleton. It mediates filopodia formation under the control of Rho-family GTPases. BAIAP2 is expressed in the cytoplasm and links small membrane-bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It has also been identified as interacting with the dentatorubral- pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Source: Recombinant protein corresponding to aa1-522 of human BAIAP2, fused to His-tag at C-terminal expressed in E. coli. Molecular Weight: ~58.4kD Amino Acid Sequence: MSLSRSEEMH RLTENVYKTI MEQFNPSLRN FIAMGKNYEK ALAGVTYAAK GYFDALVKMG ELASESQGSK ELGDVLFQMA EEMLKSFHNE LLTQLEQKVE LDSRYLSAAL KKYQTEQRSK GDALDKCQAE LKKLRKKSQG SKNPQKYSDK ELQYIDAISN DGYKTALTEE RRRFCFLVEK QCAVAKNSAA YHSKGKELLA QKLPLWQQAC ADPSKIPERA VQLMQQVASN GATLPSALSA IPGAKPLPVP PELAPFVGRM SAQESTPIMN GVTGPDGEDY SPWADRKAAQ PKSLSPPQSQ SKLSDSYSNT LPVRKSVTPK TLPRSSSMAA GLERNGRMRV KAIFSHAAGD NSTLLSFKEG DLITLLVPEA RDGWHYGESE KTKMRGWFPF SYTRVLDSDG GKSSSTGNLL DKDDLAIPPP DYGAASRAFP AQTASGFKQR PYSVAVPAFS QGLDDYGARS MSSGSGTLVS TVVEHHHHHH EVHRQIQNQL KQGELENYVS SKSNLVISDP NSYATTAENK SDRLHMSLQQ Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
