BMPR1B, Recombinant, Human, aa14-126, His-Tag (Bone morphogenetic protein receptor type-1B isoform b)

Catalog Number: USB-349731
Article Name: BMPR1B, Recombinant, Human, aa14-126, His-Tag (Bone morphogenetic protein receptor type-1B isoform b)
Biozol Catalog Number: USB-349731
Supplier Catalog Number: 349731
Alternative Catalog Number: USB-349731-20,USB-349731-100
Manufacturer: US Biological
Category: Molekularbiologie
BMPR1B also known as bone morphogenetic protein receptor type-1B isoform b. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Its receptor for BMP7/OP-1 and GDF5. Source: Recombinant protein corresponding to aa14-126 of human BMPR1B, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~15.1kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHR Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 15.1
NCBI: 001243723
Purity: ~80% (SDS-PAGE)
Form: Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 0.1mM PMSF, 20% glycerol.