CD2, Recombinant, Human, aa25-209, His-Tag (T-cell surface antigen CD2)
Catalog Number:
USB-349765
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| Article Name: | CD2, Recombinant, Human, aa25-209, His-Tag (T-cell surface antigen CD2) |
| Biozol Catalog Number: | USB-349765 |
| Supplier Catalog Number: | 349765 |
| Alternative Catalog Number: | USB-349765-100, USB-349765-500 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| CD2, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms. Recombinant protein corresponding to aa25-209 of human CD2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~23.8kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKEITNA LETWGALGQD INLDIPSFQM SDDIDDIKWE KTSDKKKIAQ FRKEKETFKE KDTYKLFKNG TLKIKHLKTD DQDIYKVSIY DTKGKNVLEK IFDLKIQERV SKPKISWTCI NTTLTCEVMN GTDPELNLYQ DGKHLKLSQR VITHKWTTSL SAKFKCTAGN KVSKESSVEP VSCPEKGLD Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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