CLIC4, Recombinant, Human, aa1-253, His-Tag (Chloride intracellular channel protein 4)
Biozol Catalog Number:
USB-349797
Supplier Catalog Number:
349797
Alternative Catalog Number:
USB-349797-100,USB-349797-500
Manufacturer:
US Biological
Category:
Molekularbiologie
CLIC4 (chloride intracellular channel 4), also known as H1, CLIC4L or MTCLIC, is a 253aa single- pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 functions as a monomer that is able to form selective ion channels in target proteins, thereby facilitating the transport of chloride and other ions. CLIC4 is thought to play a role in apoptosis and has been shown to translocate to the nucleus under stress conditions. Source: Recombinant protein corresponding to aa1-253 of human CLIC4, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~30.9kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MALSMPLNGL KEEDKEPLIE LFVKAGSDGE SIGNCPFSQR LFMILWLKGV VFSVTTVDLK RKPADLQNLA PGTHPPFITF NSEVKTDVNK IEEFLEEVLC PPKYLKLSPK HPESNTAGMD IFAKFSAYIK NSRPEANEAL ERGLLKTLQK LDEYLNSPLP DEIDENSMED IKFSTRKFLD GNEMTLADCN LLPKLHIVKV VAKKYRNFDI PKEMTGIWRY LTNAYSRDEF TNTCPSDKEV EIAYSDVAKR LTK Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
