COTL1, Recombinant, Human, aa1-142, His-Tag (Coactosin-like protein)

Product Overview

• Article Name: COTL1, Recombinant, Human, aa1-142, His-Tag (Coactosin-like protein)
• Biozol Catalog Number: USB-349810
• Supplier Catalog Number: 349810
• Alternative Catalog Number: USB-349810-100, USB-349810-500
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

COTL1 is one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. COTL1 Binds to F-actin in a calcium-independent manner and has no direct effect on actin depolymerization. Recombinant protein corresponding to aa1-142 of human COTL1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~18.1kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MATKIDKEAC RAAYNLVRDD GSAVIWVTFK YDGSTIVPGE QGAEYQHFIQ QCTDDVRLFA FVRFTTGDAM SKRSKFALIT WIGENVSGLQ RAKTGTDKTL VKEVVQNFAK EFVISDRKEL EEDFIKSELK KAGGANYDAQ TE Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 18.1
• NCBI: 066972
• UniProt: Q14019
• Purity: 90% (SDS-PAGE). Purified by using conventional chromatography techniques.
• Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 0.1M sodium chloride, 10% glycerol.