COX5A, Recombinant, Human, aa42-150, His-Tag (Cytochrome c Oxidase Subunit Va)
Biozol Catalog Number:
USB-349811
Supplier Catalog Number:
349811
Alternative Catalog Number:
USB-349811-100, USB-349811-500
Manufacturer:
US Biological
Category:
Molekularbiologie
COX5A, also known as COX, COX-VA and VA, belongs to the cytochrome c oxidase subunit 5A family. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX5A is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Source: Recombinant protein corresponding to aa42-150 of human COX5A, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~14.9kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSSHGSQET DEEFDARWVT YFNKPDIDAW ELRKGINTLV TYDMVPEPKI IDAALRACRR LNDFASTVRI LEVVKDKAGP HKEIYPYVIQ ELRPTLNELG ISTPEELGLD KV Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
