DCUN1D2, Recombinant, Human, aa1-259, His-Tag (Defective in cullin neddylation protein 1, DCN1-like protein 2)
Biozol Catalog Number:
USB-349844
Supplier Catalog Number:
349844
Alternative Catalog Number:
USB-349844-100, USB-349844-500
Manufacturer:
US Biological
Category:
Molekularbiologie
DCN1-like protein 2, also known as DCuN1D2, which contains one DCuN1 domain and 1 uBA-like domain, may play a role in the neddylation of cullins that regulate SCF-type ubiquitin ligase complexes. The gene encoding Dcun1D2 exists on human chromosome 13. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. . Source: Recombinant protein corresponding to aa1-259 of human DCuN1D2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~32.3kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MHKLKSSQKD KVRQFMACTQ AGERTAIYCL TQNEWRLDEA TDSFFQNPDS LHRESMRNAV DKKKLERLYG RYKDPQDENK IGVDGIQQFC DDLSLDPASI SVLVIAWKFR AATQCEFSRK EFLDGMTELG CDSMEKLKAL LPRLEQELKD TAKFKDFYQF TFTFAKNPGQ KGLDLEMAVA YWKLVLSGRF KFLDLWNTFL MEHHKRSIPR DTWNLLLDFG NMIADDMSNY DEEGAWPVLI DDFVEYARPV VTGGKRSLF Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
