DNAJC19, Recombinant, Human, aa19-116, His-Tag (Mitochondrial import inner membrane translocase subunit TIM14)

Product Overview

• Article Name: DNAJC19, Recombinant, Human, aa19-116, His-Tag (Mitochondrial import inner membrane translocase subunit TIM14)
• Biozol Catalog Number: USB-349857
• Supplier Catalog Number: 349857
• Alternative Catalog Number: USB-349857-100, USB-349857-500
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Recombinant protein corresponding to aa19-116 of human DNAJC19, fused to His-tag at N-terminal expressed in E. coli. Swiss/Uniprot Accession: Q96DA6 Molecular Weight: ~15.1kD Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMGRY VLQAMKHMEP QVKQVFQSLP KSAFSGGYYR GGFEPKMTKR EAALILGVSP TANKGKIRDA HRRIMLLNHP DKGGSPYIAA KINEAKDLLE GQAKK Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 15.1
• NCBI: 660304
• UniProt: Q96DA6
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.