GAP43, Recombinant, Human, aa1-238, His-Tag (Growth associated protein 43)
Biozol Catalog Number:
USB-349932
Supplier Catalog Number:
349932
Alternative Catalog Number:
USB-349932-20,USB-349932-100
Manufacturer:
US Biological
Category:
Molekularbiologie
Growth associated protein 43, also known as GAP43, is a phosphoprotein of the presynaptic membrane involved in synaptic reorganization and neural development. It is present at high levels in neuronal growth cones during development and axonal regeneration. GAP43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. Also, GAP43 plays an essential role in the maintenance mechanism of long-term potentiation (LTP). Source: Recombinant protein corresponding to aa1-238 of human GAP43, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~27.3kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMLCCMR RTKQVEKNDD DQKIEQDGIK PEDKAHKAAT KIQASFRGHI TRKKLKGEKK DDVQAAEAEA NKKDEAPVAD GVEKKGEGTT TAEAAPATGS KPDEPGKAGE TPSEEKKGEG DAATEQAAPQ APASSEEKAG SAETESATKA STDNSPSSKA EDAPAKEEPK QADVPAAVTA AAATTPAAED AAAKATAQPP TETGESSQAE ENIEAVDETK PKESARQDEG KEEEPEADQE HA Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
