MAFK, Recombinant, Human. aa1-156, His-Tag (Transcription factor MafK)
Catalog Number:
USB-350055
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| Article Name: | MAFK, Recombinant, Human. aa1-156, His-Tag (Transcription factor MafK) |
| Biozol Catalog Number: | USB-350055 |
| Supplier Catalog Number: | 350055 |
| Alternative Catalog Number: | USB-350055-100,USB-350055-500 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| MAFK belongs to the bZIP family and Maf subfamily. Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. Small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Recombinant protein corresponding to aa1-156 of human MAFK, fused to His-Tag at N-terminal, expressed in E. coli. Uniprot/Swiss Accession: NP_002351 Molecular Weight: ~19.7kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MTTNPKPNKA LKVKKEAGEN APVLSDDELV SMSVRELNQH LRGLTKEEVT RLKQRRRTLK NRGYAASCRI KRVTQKEELE RQRVELQQEV EKLARENSSM RLELDALRSK YEALQTFART VARGPVAPSK VATTSVITIV KSTELSSTSV PFSAAS Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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