NUDT16, Recombinant, Human, aa1-195, His-Tag (Nudix type motif 16)
Biozol Catalog Number:
USB-350139
Supplier Catalog Number:
350139
Alternative Catalog Number:
USB-350139-20,USB-350139-100,USB-350139-500
Manufacturer:
US Biological
Category:
Molekularbiologie
NuDT16 is nuclear nucleoside diphosphatase proteins localized within foci in the nucleolus and nucleoplasm. This is a RNA-decapping enzyme that binds specifically to u8 snoRNA. It can remove m7G and m227G caps from RNAs, rendering them substrates for 5-3 exonucleases for degradation in vivo. Recombinant protein corresponding to aa1-195 of human NUDT16, fused to His-tag at N-terminal expressed in E. coli. Uniprot/Accession: NP_689608 Molecular Weight: ~23.4kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAGARRLELG EALALGSGWR HACHALLYAP DPGMLFGRIP LRYAILMQMR FDGRLGFPGG FVDTQDRSLE DGLNRELREE LGEAAAAFRV ERTDYRSSHV GSGPRVVAHF YAKRLTLEEL LAVEAGATRA KDHGLEVLGL VRVPLYTLRD GVGGLPTFLE NSFIGSAREQ LLEALQDLGL LQSGSISGLK IPAHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.