Peptidylprolyl Isomerase F (PPIF) Recombinant, Rat, aa30-206, His-Tag
Biozol Catalog Number:
USB-350184
Supplier Catalog Number:
350184
Alternative Catalog Number:
USB-350184-100,USB-350184-500
Manufacturer:
US Biological
Category:
Molekularbiologie
Ppif also known as Peptidyl-prolyl cis-trans isomerase F, mitochondrial. Ppif accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis the requirement of the PPIase activity for this function is debated. Source: Recombinant protein corresponding to aa30-206 of rat Ppif, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~21.2kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSCSDGGAR GANSSSQNPL VYLDVGADGQ PLGRVVLELK ADVVPKTAEN FRALCTGEKG FGYKGSTFHR VIPAFMCQAG DFTNHNGTGG KSIYGSRFPD ENFTLKHVGP GVLSMANAGP NTNGSQFFIC TIKTDWLDGK HVVFGHVKEG MDVVKKIESF GSKSGKTSKK IVITDCGQLS Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
21.2
NCBI:
E. coli
Purity:
~90% (SDS-PAGE)
Form:
Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 10% glycerol.
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